1 minute read
Mar. 14, 2023
Voxelotor: a First-In-Class, Reversible Covalent Aldehyde Drug
GBT/Pfizer HbS polymerization inhibitor
FIC, oral, QD, reversible covalent HbS pol. inhibitor accelerated FDA approval for hemolytic anemia in SCD opt. + SBDD of natural product (5HMF) analogs voxelotor (GBT440, OXBRYTA) Global Blood Therapeutics, SSF, CA / Pfizer, NY
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