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Feb. 9, 2022

Giredestrant (GDC-9545): an Oral Selective Estrogen Receptor Degrader and Full Antagonist

Genentech ER Degrader

selective ER degrader (SERD) + full antag. oral (30 mg QD), Ph. III for ER+, HER2- BC from profiling >4k cmpds for desired MoA giredestrant (GDC-9545) Genentech, South San Francisco, CA

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